Hydroquinone + Tretinoin

Efficacy

Outcome				Grade		Effect		Evidence		Studies
Melasma				E		🠫 Slight		★★ Some		1 study 319 participants

Side Effects

Outcome			Effect		Frequency			Studies
Itching			⇧ Increase		22% (34 out of 158 participants)			1 study
Peeling			⇧ Increase		61% (97 out of 158 participants)			1 study
Skin Hydration			⇩ Decrease		13% (21 out of 158 participants)			1 study
Skin Redness			⇧ Increase		44% (69 out of 158 participants)			1 study
Skin Discomfort			⇧ Increase		23% (36 out of 158 participants)			1 study

Latest Research